Adrian Dunbar guest presents the second episode of the 61st series - his first appearance on the programme. Joining the Line Of Duty actor is comedian Katherine Ryan (now her eighth appearance on the show) and The Sunday Times's Political Editor Tim Shipman.
Alexander Armstrong takes to the guest host's chair for the 36th time, more than any other guest host. Meanwhile Joe Lycett makes his debut on the programme, and Newsnight presenter Kirsty Wark appears too.
Richard Ayoade guest presents - his sixth time in the host's chair. Joining the actor and comedian as the two guest panellists are broadcaster and writer Richard Osman and the former co-chairwoman of the Conservative Party, Baroness Warsi.
Aisling Bea takes to the host's chair for her programme debut. Ian and Paul are joined by comedian and actor Roisin Conaty & BBC newsreader and the recently-announced new host of Mastermind, Clive Myrie.