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For this two-hour bonanza in aid of Great Ormond Street Hospital Children's Charity, Channel 4 recently assembled 24 of Britain's best comedians to perform in front of a live audience at the O2 arena in London. So - deep breath - Jack Dee, Andy Parsons, David Mitchell, Fonejacker, Jack Whitehall, Jo Brand, James Corden, Jason Manford, John Bishop, Kevin Bridges, Kevin Eldon, Lee Evans, Mark Watson, Michael McIntyre, Noel Fielding, Patrick Kielty, Rich Hall, Rob Brydon, Ruth Jones, Sean Lock, Catherine Tate and Shappi Khorsandi take turns on stage to make it the biggest live stand-up show in British history. If that's not enough for you, Alan Carr and Bill Bailey perform with Stomp and Ricky Gervais, Stephen Merchant and Johnny Depp provide additional sketches.

Now here's a treat for an Easter Monday night; just as you look back fondly on the four-day bank holiday weekend and look forward not too fondly to returning to work tomorrow, Channel 4 have taken it upon themselves to cheer you up. They've skimmed the cream of comedy talent for a gala night dedicated to making us laugh, while raising funds for the Great Ormond Street Hospital's Children's Charity. The night will fund two new anaesthetic rooms, allowing parents to stay with their children right up until they enter the operating theatre. Make sure you watch tomorrow's brilliant documentary, Great Ormond Street (9pm BBC2), to get some idea of the astonishing work done at the hospital. The cast of comics is a glittering one: David Mitchell, Bill Bailey, Catherine Tate, Jack Dee, James Corden, Jo Brand, Jonathan Ross and many, many others will perform stand-up routines in front of a capacity crowd at the massive O2 Arena in London. As a nice little bonus, Robert Webb, Ricky Gervais, Derren Brown and Johnny Depp, who can't be there in person, have filmed comic sketches especially for the night.

Great Ormond Street Hospital is the recipient of this fundraising gala - the biggest live stand-up concert in UK history. And they couldn't have asked for more from the roster of stars who each donated five minutes last week at London's O2 Arena. Some hefty editing will be needed to get this show down to the two-hour running time it's been allotted and if the rude bits from Jonathan Ross and Mark Watson end up on the cutting room floor, then they may survive in the DVD which goes on sale on April 26.

Among those who'll definitely make the cut are, in no particular order, Michael McIntyre, Jack Dee, Bill Bailey, Kevin Eldon, Jason Manford, Jo Brand, Sean Lock and Noel Fielding.

The evening opens with a raucous dance number from Stomp and closes with a legendary performance from Lee Evans, looking the grand old man of stand-up in every sense.

This stand-up comedy show at the O2 Arena in London features a barnstorming roll-call of British comedians all stepping up to the mic in aid of Great Ormond Street Hospital Children's Charity. The bill includes Alan Carr, Bill Bailey, Catherine Tate, David Mitchell, The Fonejacker, Jack Dee, Jo Brand, Lee Evans, Michael McIntyre, Noel Fielding, Patrick Kielty, Rich Hall, Rob Brydon and Shappi Khorsandi. If you can't find somebody in that list who makes you laugh, it's possible that you have, indeed, had all your funny bones surgically removed.

For the uninitiated, The Museum of Curiosity is presented by comedy producer/godlike genius John Lloyd, and he's joined by a different 'curator' each series; Bill Bailey, Sean Lock and now the brilliant Jon Richardson. Three contributors - comedians, scientists, authors, historians, generally fascinating people - donate something the museum each week, and that something can be absolutely anything, no matter how huge, tiny, fictional or dead. I won't give away what Shappi Khorsandi, Terry Pratchett and Marcus Chown ("cosmology consultant of New Scientist") gave to the museum in the episode I saw recorded, but I will say that all three spoke passionately about their donation, and that Chown's made my brain hurt for days. The series will air later in the Spring.

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