Pye's lengthy list of credits include panel shows such as Have I Got News For You and 8 Out Of 10 Cats, as well as The Increasingly Poor Decisions Of Todd Margaret, A Young Doctor's Notebook and Respectable.
His daughter was born in 2006 with an extremely rare and, to date, undiagnosed chromosomal disorder.
The BBC explains: "Each episode shines a light on day-to-day life with Rosie - unique experiences from simply trying to take her to the park to trying to explain that every day isn't her birthday.
"A second timeline in 2006 shows the effect having a severely disabled child had on the family unit, and how it threatened to disintegrate but ultimately brought them even closer."
Filming begins next month and the series is likely to be broadcast later this year on BBC Four.
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