Siblings is about the world's worst brother and sister. Obnoxious, lazy, self-centred, underachieving, incompetent and occasionally depraved, they cause chaos and disaster wherever they go.

Each week, through their own selfishness and idiocy, we see them spectacularly wreck the lives of those around them - old friends, love interests, family members, and the unlucky individuals who just happen to cross their paths.