Dr Mu uses his dastardly shrinking technology to take over and control Queen Gertrude of Genovia. Luckily, Rufus is on hand. But will things run smoothly?

Confusion reigns on Earth as Queen Gertrude of Genovia sacks her cabinet, invites all the world's leaders to attend a conference at her palace and starts behaving very strangely. It soon emerges that Dr Mu has shrunk himself down to the size of a single bacteria, transported himself into her body and is now controlling her!

Rufus, who has sneaked on board Mu Force One and overheard the doctor's scheme, decides to go after him. Inside the Queen's body he teams up with a pair of Royal brain-cells who have been evicted from the Royal brain by Dr Mu. Together they set off on an incredible journey around the Queen's body. But when the Queen's yappy little dog arrives in the Palace, things don't go quite according to plan...