Bristow is an adaptation of the comic strip of the same name by Frank Dickens, starring Michael Williams in the title role.

Bristow is a buying clerk (18th in line for Chief Buyer) working for the Chester-Perry organisation (the company's boss, Sir Reginald Chester-Perry, is never seen), who dreaming of grander things. Hoping the world is listening, he gives his opinions on life to anyone around, and if no one is around, is quite happy talking to himself.

Bristow's work colleagues include friend Jones (although he claims to be 18th in line for Chief Buyer), Miss Purdy the tea lady, and fearsome boss Fudge.