At Thanksgiving, the Blake family gathers at the run-down Manhattan apartment in Chinatown of Brigid Blake and her boyfriend Richard. Brigid's parents arrive for dinner with Brigid, Richard and Aimee, their other adult daughter. Brigid is a musician and Aimee is a lawyer living in Philadelphia. Aimee has broken up with her girlfriend and has developed an intestinal ailment. Also present is Brigid and Aimee's grandmother, Fiona or 'Momo', who has Alzheimer's disease. Their parents are unhappy their daughters have left home and abandoned their religion. The family deals with ageing, illness and an ever changing economy.