Writer William Rose claimed the idea for The Ladykillers came to him in a dream. His work was nominated for an Oscar for "Best Screenplay".
Rose did not see the film until 1958, when he admitted that whilst the denouement had been "ruined", the film was better than his original outline.
The Ladykillers was the last film made in Britain using Technicolor's 3-strip film system.
Some interpretations of the film have the entire escapade, up until Mrs. Wilberforce's final scene of explanation in the police station, taking place in her suggestible, over-active imagination.