Jack Dee has been winning hearts and minds as the new host of I'm Sorry I Haven't a Clue. Enough words have been spoken about the totemic Humphrey Lyttelton, so I'll not weigh them up here. But on the self-titled "antidote to panel games", Dee is the perfect antidote to the cloying comfiness of the audience clapping along to "one song to the tune of another". You're left with the distinct impression that he's flashing them a trademark pitying sneer, and it's like a palate cleanser, allowing you to enjoy the craftsmanship of panelists Cryer, Garden, Brooke-Taylor and, this week, Toksvig.

Jack Dee is perfect host for I'm Sorry I Haven't a Clue

The grumpy comic has taken over from the late Humphrey Lyttleton and proved a hit. But are some presenters simply irreplaceable?

By chance, John Humphrys asking "Would you like a turn?" featured as one of the Questions That Are Never Asked on the new series of I'm Sorry I Haven't a Clue. The choice of Jack Dee to take over from the lamented Humphrey Lyttleton was an inspired one, even if his first joke about Jacqui Smith's husband destroying her career "single-handed" did sound a lot like The News Quiz. Fortunately, with the help of panellists like Barry Cryer and Graeme Garden, the programme's unique flavour remains. Like Wogan's world, the "antidote to panel games" depends a lot on the surreal, the in-joke, and the trick of being risqué without being offensive. New games like Pensioners Film Club ("Death in Fenwicks" "The Postman Always Has to Knock Twice") mixed with old favourites like One Song to the Tune of Another. The sound of Rob Brydon singing the words of Jim'll Fix it to tune of "Mad World" made me choke with laughter. The problem with in-jokes though, is that people get them too quickly. At one point Jack Dee had to issue the howling audience with a plaintive reprimand. "I have got punch lines... please wait."

These are my final radio thoughts, and I've decided to mark the occasion with a round-up of all the things I've got wrong in the period between now and the last time I did a round-up of everything I'd got wrong.

Just a Minim is not a dark new round of I'm Sorry I Haven't a Clue, invented with the sick-minded genius of grief to give the show some pzazz after Humphrey Lyttelton died. In fact, it has run since the early 80s. One reader claimed the late 70s. Nobody truly knows.

Any radio show that's just started its 51st series has to be considered a national treasure. Described as an antidote to panel games, Radio 4's I'm Sorry I Haven't A Clue may be mainly cosy, middle class comedy fare, but it's impossible not to warm to the panel's total enthusiasm - including Barry Cryer and Victoria Wood - and eagerness with which the live audience boos and claps at every opportunity. Now using rotating chairmen, after the death of Humphrey Lyttelton last year, Stephen Fry sets the bar high here for those following, clearly relishing the banter he has with his quick-witted colleagues. Criticising such an institution may be tantamount to heresy, but adding 15 minutes to the 30 wouldn't do any harm.

No Humph, no Samantha, but plenty of quality smut

After a decent interval following the death of Humphrey Lyttelton a year ago, I'm Sorry I Haven't a Clue returned with a knowing wink and a helpless giggle. It's taken three men to replace the great man, and on Monday Stephen Fry was in the Humph seat. (He'll rotate with Rob Brydon and Jack Dee, though I'd like to have seen Bill Bailey given a shot, too.)

There was a fear that reconvening without the show's spiritual leader might be like The Beatles re-forming after John Lennon died. But though Fry was berated in some quarters after his debut, the essence of the complaints was that he's not Lyttelton. He probably can't play the trumpet, either.

The Lyttelton lacuna apart, it was business as usual, with the innuendo quotient maintained at its traditionally ferocious level. The lovely Samantha has been given a rest (for newcomers, she's the non-existent scorer) in favour of "the rippling Sven", who's had the builders round: "Whenever they ask for cheese and chutney, he always palms them off with relish."

Video: Popular Radio 4 comedy returns

The much-loved Radio 4 comedy I'm Sorry I Haven't a Clue is returning to the airwaves after the death of its chairman Humphrey Lyttleton last year.

Graham Satchell went to a recording of the show in Newcastle, with Rob Brydon putting in an appearance as guest chairman.

Stephen Fry: the day the comedian became Humphrey Lyttleton

I'm Sorry I Haven't A Clue returns to Radio 4 on Monday without the late Humphrey Lyttleton. Catherine Gee attends a live recording of the panel show.

I'm Sorry I Haven't a Clue after Humphrey Lyttelton

The 'antidote to panel games' returns after the death of its chairman, Humphrey Lyttelton.