Futureproof will follow Jamali as he meets "the people finding new ways to sell sex, become celebrities - and maybe even change the world".
The producers explain: "In a crazy, scary, unpredictable new world where there are no certainties and everything is changing, online businesses, social media and the internet have ripped up the rulebook and opened the doors to a whole new way of making a living.
"But some people are embracing the change - not just riding the wave but diving headlong into it as they find new ways to flourish and thrive, reinventing reality and creating new opportunities for themselves and those around them.
"Jamali will meet surprising and wonderful characters, encounter curious and offbeat ideas and meet groups brought together by their own unique take on the world."
In total, three hour-long episodes are being filmed. Each will focus on a different theme: Sex, Fame and Cryptocurrency.
Maddix has made a name for himself presenting documentaries, with critical acclaim for his Viceland series Hate Thy Neighbour in which he travels around the world to meet extremists.
Speaking about the new show, producers Acme Films says: " With warmth, humour and an ever-inquisitive spirit, Jamali will throw himself into the unregulated no man's land of the new digital frontier to meet the workers, wannabes and visionaries creating a new world order on the digital frontline of sex, money and fame in a rebooted Reality 3.0."
Alf Lawrie from Channel 4 says: "We're absolutely thrilled to be working with Jamali. He's a perfect fit for Channel 4 - inquisitive, charming, funny, and utterly fearless - and we can't wait to let him loose on this eye-opening new series."
Futureproof will be shown on Channel 4 later this year.
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