She added: "So much has happened to us all, as mothers and women, there's a lot that is funny about where we are now. There are years of pain to draw on."
However, it is not yet known whether Channel 4 executives will be interested in reviving the series. Mackichan commented: "We will have to wait and see what happens and whether they will want to bring it out of the stable. But we would love to get the old nag out again."
She added: "It requires a lot of writing, but we have always been accosted by people who say they want it to come back and so many people have their favourite Smack The Pony sketch. Whenever it is repeated I get recognised more in the street."
Smack The Pony ran for 23 episodes across three series between 1999 and 2003, with regular themes running amongst many one-off sketches including The Oblivious Women, Irritating Flatmate and Dating Agency Videos.
Doon Mackichan was talking to The Radio Times to promote Quick Cuts, her new BBC Four sitcom, which starts next week. Mackichan is also due to appear in the Toast Of London series and in the autumn will head to Bulgaria to film the second series of ITV2 sitcom Plebs.