A major e-mail mishap leads to an exodus of clients from Eddy's business. Whilst she struggles to salvage a morsel from her TV and PR enterprises, Patsy is diagnosed with osteoporosis, and Saffy forces the pair to attend a meeting of Menopause Anonymous.

Edina's PR business is on its last legs after Bubble manages to e-mail the entirety of Eddy's private correspondence to everyone in her address book. Edina's arch-rival Claudia Bing wastes no time in picking up her clients and trying to buy her out.

Meanwhile, osteoporosis kicks in for Patsy, who is pleased to learn that she has the lowest bone density on record. Saffron invites a menopause support group to the house and forces Edina and Patsy to attend, terrified of a vision she has of the pair in the future - needy, falling apart but still hedonistic.

Edina decides that the only way to save her business is to sell off the television company. Claudia Bing is shocked and impressed when she learns of 'Radical TV' and quickly buys Katy Grin's half of the company when Katy announces her intention to sell.

Eddy shrewdly manages to flog off her half of the company, which currently has no programmes, to Claudia in return for a hefty sum and the return of several key PR clients. With business back on track, Edina celebrates with Patsy, whose hormone tablets have made her much homelier.

Saffron has a terrifying nightmare of Patsy threatening to impregnate herself with a vial of Mick Jagger's sperm unless she is allowed to move in to the house, but wakes to find that Edina and Patsy are back to their old selves.