Professor Brian Cox and comedian Robin Ince are joined by Frank Skinner, Professor Sophie Scott and Professor Richard Wiseman as they look at the science of what makes us laugh.

Brian Cox and Robin Ince return for a new series of science/comedy chat. They are joined on stage, appropriately enough, by comedian Frank Skinner, as they look at the science of what makes us laugh, why we laugh at all, and whether humour and laughter are uniquely human traits.

Joining the panel are experts in what makes us chuckle, Professor Sophie Scott and Professor Richard Wiseman. They look at why laughter is not only an ancient human trait that goes a long way to making us the social animal we are today, but that rats and apes also enjoy a good chuckle.

They discover whether science can come up with the perfect joke and why a joke with the punchline "quack" is funnier than one with the punchline "moo".