A six-part series set in the Cardiff district of the same name, Splott will follow single mother and school cook Mandy.
The BBC says: "When life gets tough Mandy turns to her bonkers neighbour Val, and her sweet but serial-killer obsessed colleague Kathleen. A passionate, sometimes gung-ho, but big hearted Mandy simply seeks peace, romance and happiness... none of this comes her way without a fight."
Ruth Jones says: "Let's be honest, who can't help but love the name Splott. A name made more loveable by the fact that it's a real place nestled in the heart of Wales's capital. I'm so excited to be playing a strong gutsy Cardiffian in what I hope is going to be a refreshingly daft and silly sitcom on Radio Wales."