McDonald announced her departure last week from the formats which she has presented for nearly half a decade.
Calman, who already hosts the Channel 5 series Secret Scotland With Susan Calman will now be "exploring the high seas and popular holiday destinations" via Cruising With Susan Calman and Holidaying With Susan Calman.
The comedian says: "I'm over the moon to be working with Channel 5 on such a prestigious group of shows.
"I can't wait to go on exciting voyages and incredible journeys and take the wonderful viewers with me. It's the start of a magnificent chapter and I can't wait to get going."
"I have encouraged her to make both shows uniquely hers and I am genuinely excited to see how she evolves them in her own, inimitable style. The world is, literally, her oyster and I can't wait to travel it with her."
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